SCHEMBL7644223

SCHEMBL7644223

C=[Zr](C)(Cl)(Cl)(CCC)(C1C=Cc2ccccc21)C1C=Cc2ccccc21

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 1/20 0.32
HTR2A P28223 1/20 0.32
SIGMAR1 Q99720 4/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7640273 0.88 HTR2A (0.33) HTR6HTR2ASIGMAR1
SCHEMBL7641664 0.86 HTR6 (0.36) HTR6HTR2ASIGMAR1
SCHEMBL7641915 0.84 HTR6 (0.34) HTR6HTR2ASIGMAR1
SCHEMBL936685 0.80 SIGMAR1 (0.34) HTR6HTR2ASIGMAR1
SCHEMBL3645746 0.80 HTR6 (0.37) HTR6HTR2ASIGMAR1
SCHEMBL4428760 0.74 HTR2A (0.33) HTR6HTR2ASIGMAR1
SCHEMBL721748 0.74 HTR2A (0.33) HTR6HTR2ASIGMAR1
SCHEMBL797197 0.73 KDM4E (0.33) HTR6HTR2ASIGMAR1
SCHEMBL7766805 0.71 HTR2A (0.35) HTR6HTR2ASIGMAR1
SCHEMBL6463578 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6472490-B1 AN ETHYLENE-AROMATIC VINYL COMPOUND COPOLYMER HAVING AN AROMATIC VINYL COMPOUND CONTENT OF FROM 1 TO LESS THAN 55% BY MOLAR FRACTION, WHICH HAS A HAZE OF AT MOST 41.5% WHEN MOLDED; METHINE DYES DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-10-29 US disclosed
US-6348556-B1 COORDINATION CATALYST OF TRANSITION METAL COMPLEX CONTAINING INDENYL GROUP(S) AND COCATALYST; ISOTACTIC; CATALYSIS, ADDITION COPOLYMERIZATION DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2002-02-19 US disclosed
US-6066709-A Ethylene-aromatic vinyl compound copolymer and method for its production DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 2000-05-23 US disclosed
US-5883213-A STEREOREGULARITY DENKI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1999-03-16 US disclosed