Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.34 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.34 |
| ▸ | SCN8A | Q9UQD0 | 5/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 5/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.32 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.32 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.32 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.32 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL765828 | 0.93 | BDKRB1 (0.42) | BDKRB1SCN8ASCN10AGAAL3MBTL1 | |
| SCHEMBL10121111 | 0.82 | BDKRB1 (0.37) | BDKRB1MAPK14PTGER4PTGER2ALDH1A1 | |
| SCHEMBL765551 | 0.79 | BDKRB1 (0.35) | BDKRB1MAPK14PTGER4PTGER2ALDH1A1 | |
| SCHEMBL764476 | 0.79 | BDKRB1 (0.35) | BDKRB1MAPK14PTGER4PTGER2ALDH1A1 | |
| SCHEMBL764433 | 0.79 | BDKRB1 (0.38) | BDKRB1MAPK14 | |
| SCHEMBL10121216 | 0.79 | BDKRB1 (0.41) | BDKRB1MAPK14PTGER4PTGER2HTT | |
| SCHEMBL765844 | 0.78 | BDKRB1 (0.42) | BDKRB1MAPK14PTGER4PTGER2 | |
| SCHEMBL765818 | 0.78 | BDKRB1 (0.41) | BDKRB1MAPK14PTGER4PTGER2HTT | |
| SCHEMBL10121214 | 0.78 | BDKRB1 (0.40) | BDKRB1MAPK14PTGER4PTGER2 | |
| SCHEMBL10121303 | 0.77 | BDKRB1 (0.36) | BDKRB1MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2188254-B1 | NOVEL BRADYKININ B1-ANTAGONISTS | BOEHRINGER INGELHEIM INT (DE) | 2012-03-21 | — | — | EP | disclosed |