Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRHR | P34981 | 4/20 | 0.55 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | MC3R | P41968 | 1/20 | 0.46 |
| ▸ | MC1R | Q01726 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644944 | 0.87 | TRHR (0.71) | TRHR | |
| SCHEMBL4955742 | 0.87 | TRHR (0.71) | TRHR | |
| SCHEMBL14028677 | 0.87 | TRHR (0.55) | TRHRMC4RMC3RMC1R | |
| SCHEMBL8252513 | 0.82 | TRHR (0.78) | TRHR | |
| SCHEMBL8257928 | 0.81 | TRHR (0.53) | TRHR | |
| SCHEMBL8251458 | 0.80 | TRHR (0.50) | TRHR | |
| SCHEMBL19359515 | 0.79 | TRHR (0.47) | TRHR | |
| SCHEMBL19359517 | 0.79 | TRHR (0.47) | TRHR | |
| SCHEMBL8258207 | 0.79 | TRHR (0.49) | TRHR | |
| SCHEMBL2791669 | 0.79 | LMNA (0.54) | TRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2006096829-A2 | THYROTROPIN-RELEASING HORMONE ANALOGS AND METHOD OF USE | ROGER WILLIAMS HOSPITAL (US) | 2006-09-14 | — | — | WO | disclosed |