SCHEMBL7645035

SCHEMBL7645035

CC=[Zr](F)(F)(C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21)C1C(C)=Cc2c(-c3cccc4ccccc34)cccc21

nearest known ligand 0.32

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.32
MAOB P27338 1/20 0.32
CA12 O43570 2/20 0.31
CA1 P00915 2/20 0.31
CA2 P00918 2/20 0.31
CA9 Q16790 2/20 0.31
ALDH1A1 P00352 1/20 0.30
CYP2A6 P11509 1/20 0.30
DHFR P00374 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5854312 0.85 PTPN1 (0.32) CA12CA1CA2CA9ALDH1A1
SCHEMBL1131276 0.83 MAOA (0.33) MAOAMAOBCA12CA1CA2
SCHEMBL7636080 0.83 BRD4 (0.31)
SCHEMBL7199342 0.81 PTPN1 (0.33)
SCHEMBL7150484 0.80 CA12 (0.33) MAOAMAOBCA12CA1CA2
SCHEMBL139428 0.79 DHFR (0.34) MAOAMAOBCA12CA1CA2
Hydrochloric Acid SCHEMBL271719 0.79 CA12 (0.32) MAOAMAOBCA12CA1CA2
Hydrochloric Acid SCHEMBL6440146 0.79 ALDH1A1 (0.33) MAOAMAOBCA12CA1CA2
Fluoride SCHEMBL7645016 0.79 CA12 (0.32) MAOAMAOBCA12CA1CA2
Hydrochloric Acid SCHEMBL7724268 0.79 CA12 (0.32) MAOAMAOBCA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020143125-A1 Catalyst component and catalyst system having a high polymerization activity for preparing polymers KAMINSKY WALTER (DE) 2002-10-03 US disclosed
US-6303718-B1 PARTICULARLY A CATALYST SYSTEM CONSISTING OF METALLOCENE FLUORIDES AND ALUMINUM ALKYLS BAYER AKTIENGESELLSCHAFT (DE) 2001-10-16 US disclosed