Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.47 |
| ▸ | ALPI | P09923 | 2/20 | 0.47 |
| ▸ | ALPG | P10696 | 2/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.45 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650743 | 0.84 | HPGD (0.56) | HPGDKMT2ANPC1ALPLALPI | |
| SCHEMBL7648550 | 0.82 | NPC1 (0.44) | HPGDKMT2ANPC1MEN1RAB9A | |
| SCHEMBL7645749 | 0.73 | ALDH1A1 (0.34) | SMN1; SMN2 | |
| SCHEMBL12224103 | 0.73 | HPGD (0.62) | HPGDKMT2ANPC1ALPLALPI | |
| SCHEMBL7644181 | 0.72 | HPGD (0.51) | HPGDKMT2ANPC1MEN1RAB9A | |
| SCHEMBL16178580 | 0.71 | CA1 (0.44) | HPGDKMT2A | |
| SCHEMBL1433698 | 0.71 | RAB9A (0.81) | HPGDKMT2ANPC1ALPLALPI | |
| SCHEMBL7645199 | 0.71 | KDM4E (0.30) | KDM4E | |
| SCHEMBL11113311 | 0.71 | HPGD (0.59) | HPGDKMT2ANPC1ALPLALPI | |
| SCHEMBL11162047 | 0.70 | KMT2A (0.61) | HPGDKMT2ANPC1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022137-A1 | β-LACTAM ANALOGS AND USES THEREFOR | SHOICHET BRIAN K (US) | 2002-03-21 | — | — | WO | disclosed |