Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.43 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.40 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650740 | 0.82 | HPGD (0.51) | NPC1MEN1KMT2ARAB9AGAA | |
| SCHEMBL7648553 | 0.81 | GAA (0.47) | NPC1MEN1KMT2ARAB9ACRHBP | |
| SCHEMBL7644181 | 0.80 | HPGD (0.51) | NPC1MEN1KMT2ARAB9AHPGD | |
| SCHEMBL16178580 | 0.76 | CA1 (0.44) | KMT2AHPGDALDH1A1 | |
| SCHEMBL7645749 | 0.75 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL670441 | 0.75 | LIPE (0.35) | ALDH1A1LMNA | |
| SCHEMBL14873552 | 0.74 | MEN1 (0.57) | MEN1KMT2ARAB9AGAAHPGD | |
| SCHEMBL7645199 | 0.73 | KDM4E (0.30) | — | |
| SCHEMBL13701830 | 0.70 | MEN1 (0.55) | NPC1MEN1KMT2ARAB9ACRHBP | |
| SCHEMBL11165331 | 0.68 | CRHBP (0.65) | NPC1MEN1KMT2ARAB9ACRHBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002022137-A1 | β-LACTAM ANALOGS AND USES THEREFOR | SHOICHET BRIAN K (US) | 2002-03-21 | — | — | WO | disclosed |