Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GSK3A | P49840 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | FABP4 | P15090 | 1/20 | 0.36 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3300277 | 0.85 | ALDH1A1 (0.49) | KDM4EPOLBGLASMN1; SMN2EGFR | |
| SCHEMBL7058470 | 0.83 | GSK3A (0.46) | APEX1KDM4EGSK3AGSK3BGAA | |
| SCHEMBL3301756 | 0.80 | TMEM97 (0.51) | APEX1GAA | |
| SCHEMBL3300241 | 0.79 | HTR4 (0.48) | — | |
| SCHEMBL3314327 | 0.78 | POLB (0.61) | APEX1KDM4EASAH1P2RX4POLB | |
| SCHEMBL7597147 | 0.77 | POLB (0.43) | APEX1KDM4EASAH1P2RX4POLB | |
| SCHEMBL2267441 | 0.76 | KDM4E (0.47) | APEX1KDM4EPOLBSMN1; SMN2GAA | |
| SCHEMBL8947389 | 0.75 | HTR4 (0.41) | KDM4EGLAGAA | |
| SCHEMBL8947427 | 0.75 | KDM4E (0.54) | KDM4E | |
| SCHEMBL1180653 | 0.75 | POLB (0.64) | KDM4EP2RX4POLBGLASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002030886-A2 | HETEROCYCLIC ANGIOGENESIS INHIBITORS | MATTHEWS BARRY R (AU) | 2002-04-18 | — | — | WO | disclosed |