Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 3/20 | 0.33 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | PTGES | O14684 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3870123 | 0.90 | P2RX7 (0.36) | PPARGP2RX7KMT2AMEN1TDP1 | |
| SCHEMBL7069483 | 0.86 | NPSR1 (0.41) | KMT2AMAPTITGB1ITGA4NPSR1 | |
| SCHEMBL3870277 | 0.86 | PTGES (0.35) | P2RX7KMT2AMEN1TDP1MAPT | |
| SCHEMBL7327485 | 0.84 | HRH1 (0.36) | SMN1; SMN2NPSR1 | |
| SCHEMBL3868793 | 0.82 | CYP2C9 (0.43) | KMT2AMEN1SMN1; SMN2ITGB1ITGA4 | |
| SCHEMBL5690598 | 0.81 | MAPT (0.37) | KMT2AMEN1MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL7510017 | 0.81 | KDM1A (0.35) | KMT2AMEN1TDP1MAPTNPSR1 | |
| SCHEMBL7068178 | 0.80 | POLB (0.40) | KMT2AMEN1NPSR1ALDH1A1LMNA | |
| SCHEMBL3870515 | 0.80 | P2RX7 (0.34) | PPARGP2RX7KMT2AMEN1MAPT | |
| SCHEMBL5690759 | 0.78 | TRPV1 (0.41) | KMT2ATDP1MAPTSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193312-A1 | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 | ELAN PHARMACEUTICALS, INC. | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193312-A1 | Carbamyloxy compounds which inhibit leukocyte adhesion mediated by VLA-4 | VCAM1, ICAM1, L1CAM | PPARG 2344/4885P2RX7 4659/4885KMT2A 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.