Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.57 |
| ▸ | NPC1 | O15118 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 7/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | LMNA | P02545 | 5/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646718 | 0.87 | RAB9A (0.54) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7649936 | 0.86 | NPC1 (0.63) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7526018 | 0.86 | ALDH1A1 (0.52) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7526004 | 0.86 | ALDH1A1 (0.52) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7646108 | 0.85 | PTPN1 (0.51) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7646703 | 0.85 | PTPN1 (0.51) | RAB9ANPC1KMT2AMEN1MAPT | |
| SCHEMBL7648639 | 0.85 | NPC1 (0.45) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7644888 | 0.84 | PTPN1 (0.46) | KMT2AMEN1MAPTALDH1A1LMNA | |
| SCHEMBL7648595 | 0.81 | MAPT (0.40) | RAB9ANPC1KMT2AMEN1MAPK1 | |
| SCHEMBL7037519 | 0.78 | MEN1 (0.53) | RAB9ANPC1KMT2AMEN1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |