Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.63 |
| ▸ | RAB9A | P51151 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.60 |
| ▸ | MEN1 | O00255 | 7/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.47 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.47 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646106 | 0.86 | RAB9A (0.57) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7644901 | 0.85 | RAB9A (0.58) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7646346 | 0.82 | ALDH1A1 (0.53) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL2834528 | 0.81 | PTPN1 (0.73) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7646488 | 0.79 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7526766 | 0.79 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7646483 | 0.79 | KMT2A (0.55) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7526018 | 0.79 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL7526004 | 0.79 | ALDH1A1 (0.52) | NPC1RAB9AKMT2AMEN1MAPK1 | |
| SCHEMBL22196106 | 0.78 | KMT2A (0.78) | NPC1RAB9AKMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479548-B2 | P-(BENZOYLAMINO)STILBENE DERIVATIVES | TELIK, INC. | 2002-11-12 | — | — | US | disclosed |