Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.37 |
| ▸ | CTSS | P25774 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | CTSL | P07711 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646910 | 0.84 | ALDH1A1 (0.36) | PPARACTSBALDH1A1L3MBTL1LMNA | |
| SCHEMBL8026778 | 0.77 | L3MBTL1 (0.35) | PPARAALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL8618352 | 0.73 | PPARA (0.40) | PPARACTSBCTSSNPSR1PPARG | |
| SCHEMBL7648440 | 0.72 | — | — | |
| SCHEMBL6401312 | 0.72 | CA1 (0.40) | PPARACTSSNPSR1PPARGL3MBTL1 | |
| SCHEMBL7646170 | 0.71 | PPARA (0.57) | PPARACTSBCTSSPPARGCTSL | |
| SCHEMBL28233244 | 0.71 | CYP1A2 (0.41) | PPARAPPARGALDH1A1 | |
| SCHEMBL5074711 | 0.70 | MMP8 (0.42) | CTSBALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL27389520 | 0.69 | SLC1A3 (0.41) | CTSBALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL14718416 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482921-B1 | Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use | ESSENTIAL THERAPEUTICS, INC. | 2002-11-19 | — | — | US | disclosed |
| WO-2000044335-A2 | URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-08-03 | — | — | WO | disclosed |