Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.50 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.50 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.47 |
| ▸ | GPR84 | Q9NQS5 | 6/20 | 0.46 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARD | Q03181 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 6/20 | 0.46 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.46 |
| ▸ | TLR2 | O60603 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | FABP4 | P15090 | 2/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.46 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.46 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1438637 | 1.00 | ALDH1A1 (0.52) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL6386011 | 0.98 | ALDH1A1 (0.48) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL387923 | 0.91 | TSHR (0.46) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL26397513 | 0.85 | TSHR (0.52) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL28835272 | 0.83 | ALDH1A1 (0.53) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL7646384 | 0.82 | KDM4C (0.37) | ALDH1A1TSHRFFAR4FFAR1GSTK1 | |
| SCHEMBL195285 | 0.82 | — | — | |
| SCHEMBL3910329 | 0.82 | — | — | |
| Methoxymethane SCHEMBL30513284 | 0.81 | KDM4C (0.58) | ALDH1A1TSHRFFAR4FFAR1LMNA | |
| SCHEMBL30834710 | 0.81 | ALDH1A1 (0.54) | ALDH1A1TSHRFFAR4FFAR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | TALLEY JOHN J (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | NR3C1, FPR1, NR4A1 | ALDH1A1 240/4885TSHR 1653/4885FFAR4 983/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.