Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.37 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.37 |
| ▸ | GSTK1 | Q9Y2Q3 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.35 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.35 |
| ▸ | FAAH | O00519 | 4/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6386011 | 0.84 | ALDH1A1 (0.48) | GSTK1TSHRENPEPALDH1A1KMT2A | |
| SCHEMBL7646382 | 0.82 | ALDH1A1 (0.52) | GSTK1TSHRALDH1A1KMT2AFFAR4 | |
| SCHEMBL1438637 | 0.82 | ALDH1A1 (0.52) | GSTK1TSHRALDH1A1KMT2AFFAR4 | |
| SCHEMBL28085552 | 0.79 | TSHR (0.56) | TSHRFAAHCNR1CNR2ALDH1A1 | |
| SCHEMBL387923 | 0.78 | TSHR (0.46) | GSTK1TSHRENPEPALDH1A1FFAR4 | |
| SCHEMBL9185822 | 0.74 | LMNA (0.53) | PHF8KDM2ATSHRHAO1ALDH1A1 | |
| SCHEMBL9632912 | 0.74 | TBXAS1 (0.34) | KDM4CKDM4APHF8KDM2AALDH1A1 | |
| SCHEMBL6510861 | 0.74 | LDHA (0.35) | TSHRALDH1A1MAPT | |
| SCHEMBL1716672 | 0.74 | KDM4C (0.46) | KDM4CKDM4APHF8KDM2AGSTK1 | |
| SCHEMBL3910329 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | TALLEY JOHN J (US) | 2002-05-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020058691-A1 | 3,4-Diaryl Thiophenes and analogs thereof having use as antiflammatory agents | NR3C1, FPR1, NR4A1 | KDM4C 2037/4885KDM4A 1641/4885PHF8 3190/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.