Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CALM1 | P0DP23 | 1/20 | 0.39 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31652584 | 0.88 | RAB9A (0.42) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL10372971 | 0.77 | KDM4E (0.41) | KDM4EALDH1A1LMNAGAAMEN1 | |
| SCHEMBL10370972 | 0.76 | TSHR (0.48) | KDM4EALDH1A1HSD17B10LMNATSHR | |
| SCHEMBL8711671 | 0.75 | DDR2 (0.56) | KDM4EALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL7646411 | 0.74 | NQO1 (0.42) | KDM4EALDH1A1HSD17B10MEN1KMT2A | |
| SCHEMBL5579331 | 0.74 | KDM4E (0.57) | KDM4EALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL24046932 | 0.72 | MEN1 (0.64) | KDM4EALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL3865070 | 0.71 | ALDH1A1 (0.42) | KDM4EALDH1A1HSD17B10LMNAGLA | |
| SCHEMBL16794906 | 0.70 | KDM4E (0.69) | KDM4EALDH1A1HSD17B10LMNAGAA | |
| SCHEMBL1520307 | 0.70 | KMT2A (0.50) | KDM4EALDH1A1HSD17B10LMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. | 2025-07-03 | — | — | US | disclosed |
| WO-2023196538-A1 | GPR35 MODULATORS AND USES THEREOF | CROSSIGNAL THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250214976-A1 | GPR35 MODULATORS AND USES THEREOF | GPR35, GPR34, GPR68 | KDM4E 3969/4885ALDH1A1 2672/4885HSD17B10 2934/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.