Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | APEX1 | P27695 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.40 |
| ▸ | PLAU | P00749 | 1/20 | 0.40 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.40 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4081685 | 0.98 | HTT (0.52) | HTTL3MBTL1GAAPPARAPOLB | |
| SCHEMBL3562863 | 0.97 | HTT (0.47) | HTTL3MBTL1GAAPPARAPOLB | |
| SCHEMBL7646875 | 0.88 | HTT (0.66) | HTTL3MBTL1POLBAPEX1TDP1 | |
| SCHEMBL1667037 | 0.86 | HTT (0.68) | HTTL3MBTL1GAAPOLBAPEX1 | |
| SCHEMBL3626122 | 0.85 | GAA (0.59) | HTTL3MBTL1GAATP53TSHR | |
| SCHEMBL31228620 | 0.85 | GAA (0.59) | HTTL3MBTL1GAATP53TSHR | |
| SCHEMBL2039841 | 0.85 | L3MBTL1 (0.55) | L3MBTL1GAAPPARATP53TSHR | |
| SCHEMBL2203739 | 0.84 | HTT (0.61) | HTTL3MBTL1POLBAPEX1TDP1 | |
| SCHEMBL13332095 | 0.83 | L3MBTL1 (0.65) | HTTL3MBTL1GAAPOLBMAPT | |
| SCHEMBL9615211 | 0.83 | GAA (0.66) | HTTL3MBTL1GAATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6486338-B1 | Preparation of organosilicon compounds containing α, β-unsaturated carboxylic acids | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2002-11-26 | — | — | US | disclosed |