Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | APEX1 | P27695 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | PRMT1 | Q99873 | 3/20 | 0.42 |
| ▸ | F2 | P00734 | 2/20 | 0.42 |
| ▸ | ST14 | Q9Y5Y6 | 2/20 | 0.42 |
| ▸ | PLAU | P00749 | 1/20 | 0.42 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.42 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.42 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.42 |
| ▸ | TMPRSS2 | O15393 | 1/20 | 0.42 |
| ▸ | PTP4A3 | O75365 | 1/20 | 0.42 |
| ▸ | SLC22A3 | O75751 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646498 | 0.98 | HTT (0.50) | HTTGAAL3MBTL1POLBAPEX1 | |
| SCHEMBL3562863 | 0.95 | HTT (0.47) | HTTGAAL3MBTL1POLBAPEX1 | |
| SCHEMBL1667037 | 0.88 | HTT (0.68) | HTTGAAL3MBTL1POLBAPEX1 | |
| SCHEMBL31228620 | 0.87 | GAA (0.59) | HTTGAAL3MBTL1TP53TSHR | |
| SCHEMBL3626122 | 0.87 | GAA (0.59) | HTTGAAL3MBTL1TP53TSHR | |
| SCHEMBL7646875 | 0.86 | HTT (0.66) | HTTL3MBTL1POLBAPEX1TDP1 | |
| SCHEMBL9615211 | 0.85 | GAA (0.66) | HTTGAAL3MBTL1TP53TSHR | |
| SCHEMBL20810644 | 0.84 | NR5A1 (0.53) | HTTGAAL3MBTL1POLBTSHR | |
| SCHEMBL15582454 | 0.84 | RARB (0.63) | HTTL3MBTL1POLBAPEX1TDP1 | |
| SCHEMBL2039841 | 0.84 | L3MBTL1 (0.55) | GAAL3MBTL1TP53TSHRPLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1247796-B1 | Photoisomerizable compounds | MERCK PATENT GMBH (DE) | 2009-05-13 | — | — | EP | disclosed |
| US-6849203-B2 | Photoisomerizable compounds | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20020187282-A1 | Photoisomerizable compounds | MERCK PATENT (DE) | 2002-12-12 | — | — | US | disclosed |
| EP-1247796-A2 | Photoisomerizable compounds | MERCK PATENT GmbH (DE) | 2002-10-09 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020187282-A1 | Photoisomerizable compounds | CRY1, LBR, MAPRE1 | HTT 2189/4885GAA 3088/4885L3MBTL1 431/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.