SCHEMBL7653319

SCHEMBL7653319

[CH2]CCCCCc1ccccc1Oc1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
HRH1 P35367 1/20 0.59
SLC6A4 P31645 5/20 0.49
SLC6A2 P23975 2/20 0.49
RIPK1 Q13546 1/20 0.49
CYP19A1 P11511 1/20 0.41
FFAR1 O14842 1/20 0.40
THRA P10827 1/20 0.39
THRB P10828 1/20 0.39
HTR2A P28223 3/20 0.39
MGLL Q99685 1/20 0.38
SLC6A3 Q01959 1/20 0.38
MAOA P21397 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5535030 0.98 HRH1 (0.61) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL7646958 0.93 HRH1 (0.62) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL5545669 0.85 HRH1 (0.67) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL321170 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1THRA
SCHEMBL20895821 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1THRA
SCHEMBL6552750 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1THRA
SCHEMBL11524632 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL407448 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1THRA
SCHEMBL11664363 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1CYP19A1
SCHEMBL8016071 0.83 HRH1 (0.59) HRH1SLC6A4SLC6A2RIPK1THRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11981763-B2 Resin composition for stereolithographic modeling KURARAY NORITAKE DENTAL INC. (JP) 2024-05-14 US disclosed
EP-3900693-B1 USE OF A RESIN COMPOSITION KURARAY NORITAKE DENTAL INC (JP) 2024-03-20 EP disclosed
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom KURARAY CO., LTD. (JP) 2023-11-14 US disclosed
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KURARAY NORITAKE DENTAL INC. (JP) 2023-07-06 US disclosed
WO-2023127934-A1 ENERGY-RAY-CURABLE COMPOSITION FOR THREE-DIMENSIONAL SHAPING USE, DENTAL STRUCTURE, MOUTHPIECE, TEETH-STRAIGHTENING MOUTHPIECE, AND METHOD FOR PRODUCING DENTAL STRUCTURE クラレノリタケデンタル株式会社 2023-07-06 WO disclosed
WO-2023120611-A1 CURABLE DENTAL COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
WO-2023120610-A1 DENTAL CURABLE COMPOSITION クラレノリタケデンタル株式会社 2023-06-29 WO disclosed
US-11655324-B2 Resin composition for optical shaping KURARAY NORITAKE DENTAL INC. (JP) 2023-05-23 US disclosed
US-20230091071-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY KURARAY NORITAKE DENTAL INC. (JP) 2023-03-23 US disclosed
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2023-02-09 US disclosed
EP-3991958-A1 CURABLE COMPOSITION AND STEREOLITHOGRAPHIC RESIN COMPOSITION COMPRISING SAME Kuraray Co., Ltd. (JP) 2022-05-04 EP disclosed
EP-3992216-A1 CURABLE COMPOSITION, AND RESIN COMPOSITION FOR STEREOLITHOGRAPHY PREPARED THEREFROM Kuraray Co., Ltd. (JP) 2022-05-04 EP disclosed
EP-3981810-A1 RESIN COMPOSITION FOR OPTICAL SHAPING Kuraray Noritake Dental Inc. (JP) 2022-04-13 EP disclosed
US-20220041777-A1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTAL INC. (JP) 2022-02-10 US disclosed
US-20210340304-A1 RESIN COMPOSITION FOR OPTICAL SHAPING KURARAY NORITAKE DENTALI INC. (JP) 2021-11-04 US disclosed
EP-3900693-A1 RESIN COMPOSITION FOR OPTICAL MOLDING Kuraray Noritake Dental Inc. (JP) 2021-10-27 EP disclosed
EP-3862373-A1 RESIN COMPOSITION FOR OPTICAL SHAPING Kuraray Noritake Dental Inc. (JP) 2021-08-11 EP disclosed
CN-1149214-C Triazolo gerivatives and chemokine inhibitors containing the same as the active ingredient ������������ʽ���� 2004-05-12 CN disclosed
US-6492364-B1 Triazolo and derivatives as chemokine inhibitors TORAY INDUSTRIES, INC. (JP) 2002-12-10 US disclosed
EP-1067130-A1 TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT TORAY INDUSTRIES, INC. (JP) 2001-01-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11814454-B2 Curable composition, and resin composition for stereolithography prepared therefrom WASF2, COPE, ARCN1 HRH1 3453/4885SLC6A4 4523/4885SLC6A2 4778/4885
US-20230210728-A1 ENERGY RAY-CURABLE COATING MATERIAL FOR THREE-DIMENSIONAL SHAPED ARTICLES, ENERGY RAY-CURABLE MATERIAL KIT FOR THREE-DIMENSIONAL SHAPING INCLUDING SAME, THREE-DIMENSIONAL SHAPED ARTICLE USING SAME, AND METHOD OF PRODUCTION THEREOF KIT, SETD7, SETDB1 HRH1 3785/4885SLC6A4 4567/4885SLC6A2 4776/4885
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION CAD, MAT2B, RER1 HRH1 284/4885SLC6A4 4570/4885SLC6A2 4714/4885
US-20230091071-A1 RESIN COMPOSITION FOR STEREOLITHOGRAPHY MAT2B, ARCN1, COL2A1 HRH1 2883/4885SLC6A4 3371/4885SLC6A2 2974/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.