Succinamide

Succinamide

SCHEMBL7647282

CON1C(=O)CCC1=O.NC(=O)CCC(N)=O

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.36
KMT2A Q03164 1/20 0.33
ATM Q13315 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
HPGD P15428 2/20 0.33
HTT P42858 1/20 0.33
LMNA P02545 2/20 0.33
CA12 O43570 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA7 P43166 1/20 0.33
CA9 Q16790 1/20 0.33
CA13 Q8N1Q1 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL784740 0.80
SCHEMBL12284875 0.78 TSHR (0.35) TSHRL3MBTL1APEX1BLM
SCHEMBL14141320 0.73 SMN1; SMN2 (0.36) TSHRKMT2ASMN1; SMN2HPGDHTT
SCHEMBL12185672 0.73 TSHR (0.34) TSHRKMT2ASMN1; SMN2
Methoxymethane SCHEMBL7647288 0.73 KDM4E (0.40) TSHRKMT2ASMN1; SMN2HPGDHTT
SCHEMBL21846055 0.72 SMN1; SMN2 (0.38) TSHRKMT2ASMN1; SMN2HPGDHTT
SCHEMBL21846020 0.72 SMN1; SMN2 (0.38) TSHRKMT2ASMN1; SMN2HPGDHTT
SCHEMBL9634740 0.71 LMNA (0.41) TSHRLMNACA12CA1CA2
SCHEMBL13495310 0.71 BRD4 (0.40) KMT2ASMN1; SMN2LMNABLMALDH1A1
SCHEMBL13495288 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6423748-B1 CONTACT LENSES ANTISEPTIC ALCON MANUFACTURING, LTD. 2002-07-23 US disclosed
US-6316669-B1 OPHTHALMOLOGY ALCON MANUFACTURING, LTD. 2001-11-13 US disclosed
EP-1140805-A1 AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS Alcon Laboratories, Inc. (US) 2001-10-10 EP disclosed
EP-1140804-A1 BIS-AMIDO POLYBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS Alcon Laboratories, Inc. (US) 2001-10-10 EP disclosed
WO-2000035862-A1 AMIDO POLYBIGUANIDES AND THE USE THEREOF AS ANTIMICROBIAL AGENTS ALCON LABORATORIES, INC. (US) 2000-06-22 WO disclosed
WO-2000035861-A1 BIS-AMIDO POLYBIGUANIDES AND THE USE THEREOF TO DISINFECT CONTACT LENSES AND PRESERVE PHARMACEUTICAL COMPOSITIONS ALCON LABORATORIES, INC. (US) 2000-06-22 WO disclosed