Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | GMNN | O75496 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA3 | P07451 | 1/20 | 0.36 |
| ▸ | TYR | P14679 | 1/20 | 0.36 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18338 | 0.85 | CA1 (0.50) | NR1H2LMNACYP3A4MEN1MAPT | |
| SCHEMBL11022392 | 0.83 | ALOX15 (0.47) | NR1H2LMNACYP3A4MEN1MAPT | |
| SCHEMBL21679527 | 0.82 | LMNA (0.49) | NR1H2LMNAMEN1MAPTKMT2A | |
| SCHEMBL10914949 | 0.80 | NR1H2 (1.00) | NR1H2LMNACYP3A4MEN1MAPT | |
| SCHEMBL29726 | 0.80 | NR1H2 (1.00) | NR1H2LMNACYP3A4MEN1MAPT | |
| SCHEMBL9275867 | 0.79 | MAOA (0.45) | NR1H2CYP3A4MAPTHPGDHSD17B10 | |
| SCHEMBL9637010 | 0.77 | MAOA (0.47) | NR1H2LMNACYP3A4MEN1MAPT | |
| SCHEMBL9485993 | 0.77 | CYP3A4 (0.64) | NR1H2CYP3A4MEN1MAPTKMT2A | |
| SCHEMBL8089982 | 0.77 | MAOA (0.43) | NR1H2CYP3A4MAPTHPGDHSD17B10 | |
| SCHEMBL21679377 | 0.77 | NR1H2 (0.38) | NR1H2LMNACYP3A4MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6471877-B1 | Filter device for polycarbonate and production method for polycarbonate | TEIJIN LIMITED (JP) | 2002-10-29 | — | — | US | disclosed |