Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ANPEP | P15144 | 1/20 | 0.38 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.38 |
| ▸ | TRPM8 | Q7Z2W7 | 5/20 | 0.35 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.35 |
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646150 | 0.91 | SLC7A5 (0.41) | TRPM8CASRSLC7A5TP53BP1 | |
| SCHEMBL7650960 | 0.84 | RXRA (0.35) | ANPEPENPEPTRPM8MRGPRX4CASR | |
| SCHEMBL7648073 | 0.81 | SLC7A5 (0.42) | TRPM8CASRSLC7A5TP53BP1 | |
| SCHEMBL2379533 | 0.80 | ANPEP (0.42) | ANPEPENPEPMRGPRX4SLC7A5KDM4E | |
| SCHEMBL2379838 | 0.80 | ANPEP (0.42) | ANPEPENPEPMRGPRX4SLC7A5KDM4E | |
| SCHEMBL2378736 | 0.80 | ANPEP (0.42) | ANPEPENPEPMRGPRX4SLC7A5KDM4E | |
| SCHEMBL7645861 | 0.78 | L3MBTL1 (0.36) | L3MBTL1KDM4EALDH1A1 | |
| SCHEMBL7646277 | 0.76 | SLC7A5 (0.38) | CASRSLC7A5TP53BP1 | |
| SCHEMBL22467363 | 0.76 | KMT2A (0.39) | KDM4EALDH1A1LMNA | |
| SCHEMBL7647703 | 0.74 | MRGPRX4 (0.40) | MRGPRX4SLC7A5L3MBTL1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |