Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 3/20 | 0.36 |
| ▸ | CYP4A11 | Q02928 | 3/20 | 0.36 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | TRPM8 | Q7Z2W7 | 3/20 | 0.33 |
| ▸ | ACHE | P22303 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7646150 | 0.90 | SLC7A5 (0.41) | SLC7A5CASRTP53BP1TRPM8ACHE | |
| SCHEMBL7646277 | 0.85 | SLC7A5 (0.38) | SLC7A5CASRTP53BP1ACHEFAAH | |
| SCHEMBL7647701 | 0.81 | ANPEP (0.38) | SLC7A5CASRTP53BP1TRPM8 | |
| SCHEMBL7650960 | 0.77 | RXRA (0.35) | SLC7A5CASRTRPM8 | |
| SCHEMBL7646918 | 0.75 | SLC7A5 (0.44) | SLC7A5CASRCYP4F2CYP4A11TP53BP1 | |
| SCHEMBL12270167 | 0.74 | SLC7A5 (0.52) | SLC7A5CASRTP53BP1STAT3 | |
| SCHEMBL22467363 | 0.74 | KMT2A (0.39) | — | |
| SCHEMBL7648075 | 0.74 | CYP4A11 (0.53) | SLC7A5CYP4F2CYP4A11ACHE | |
| SCHEMBL7026472 | 0.73 | SLC7A5 (0.51) | SLC7A5CASRTP53BP1STAT3 | |
| SCHEMBL7504300 | 0.73 | SLC7A5 (0.51) | SLC7A5CASRTP53BP1STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002100871-A1 | NEW COMPOUNDS USEFUL IN REFLUX DISEASE | ASTRAZENECA AB (SE) | 2002-12-19 | — | — | WO | disclosed |