Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7759636 | 0.87 | ALDH1A1 (0.59) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL29588785 | 0.86 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL874473 | 0.86 | ALDH1A1 (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL6661356 | 0.81 | SMN1; SMN2 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL6573968 | 0.79 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL9250162 | 0.78 | RAB9A (0.54) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7648154 | 0.77 | ACLY (0.44) | RAB9ANPC1ALDH1A1KDM4ETDP1 | |
| SCHEMBL2340156 | 0.77 | RAB9A (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E | |
| SCHEMBL7057948 | 0.77 | CYP1A2 (0.57) | SMN1; SMN2ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL4967072 | 0.77 | ALDH1A1 (0.53) | SMN1; SMN2RAB9ANPC1ALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0797580-B1 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 2002-04-10 | — | — | EP | disclosed |
| US-5763599-A | FOR LIGHT-CONTROLLED SYNTHESIS OF OLIGONUCLEOTIDES ON DNA CHIP | Pfleiderer, Wolfgang (DE) | 1998-06-09 | — | — | US | disclosed |
| EP-0797580-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | Pfleiderer, Wolfgang (DE) | 1997-10-01 | — | — | EP | disclosed |
| WO-1996018634-A2 | NUCLEOSIDE DERIVATIVES WITH PHOTOLABILE PROTECTIVE GROUPS | PFLEIDERER WOLFGANG (DE) | 1996-06-20 | — | — | WO | disclosed |