SCHEMBL874473

SCHEMBL874473

COc1cc(COC(=O)Cl)c([N+](=O)[O-])cc1OC

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.54
KDM4E B2RXH2 4/20 0.54
SMN1; SMN2 Q16637 3/20 0.54
HTT P42858 1/20 0.54
RAB9A P51151 3/20 0.53
NPC1 O15118 2/20 0.53
TDP1 Q9NUW8 1/20 0.51
CYP2C19 P33261 3/20 0.49
CYP3A4 P08684 3/20 0.49
MEN1 O00255 1/20 0.49
KMT2A Q03164 1/20 0.49
CYP2D6 P10635 2/20 0.49
L3MBTL1 Q9Y468 2/20 0.49
MAPT P10636 2/20 0.47
CYP1A2 P05177 2/20 0.47
LMNA P02545 1/20 0.46
HPGD P15428 1/20 0.46
MTNR1A P48039 1/20 0.45
MTNR1B P49286 1/20 0.45
ALOX15 P16050 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29588785 1.00 ALDH1A1 (0.54) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL18622517 0.89 ALDH1A1 (0.45) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL26661473 0.88 RAB9A (0.56) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL8102163 0.87 ALDH1A1 (0.47) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL11593077 0.87 RAB9A (0.54) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL4075702 0.87 SMN1; SMN2 (0.54) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL11593080 0.87 SMN1; SMN2 (0.54) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL7647995 0.86 SMN1; SMN2 (0.51) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL27610152 0.86 SMN1; SMN2 (0.51) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A
SCHEMBL14733954 0.85 NPC1 (0.53) ALDH1A1KDM4ESMN1; SMN2HTTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 171 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4400166-A2 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2024-07-17 EP claimed
EP-3565484-B1 COMPOSITIONS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS CONTRALINE INC (US) 2024-04-03 EP claimed
CN-110627832-A Preparation method for synthesizing tenofovir alafenamide by oxidation method 江西农业大学 2019-12-31 CN claimed
EP-3565484-A1 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2019-11-13 EP claimed
US-10167319-B2 Caged cell penetrating peptide-polymer conjugates for diagnostic and therapeutic applications BEN-GURION UNIVERSITY OF NEGEV RESEARCH & DEVELOPMENT AUTHORITY (IL) 2019-01-01 US claimed
WO-2018129369-A1 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. (US) 2018-07-12 WO claimed
US-20180185096-A1 METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS Contraline, Inc. 2018-07-05 US claimed
US-9795675-B2 Light-activatable polymeric nanoparticles CNC — CENTRO DE NEUROCIÊNCIAS E BIOLOGIA CELULAR (PT) 2017-10-24 US claimed
US-20160220673-A1 LIGHT-ACTIVATABLE POLYMERIC NANOPARTICLES CNC - CENTRO DE NEUROCIÊNCIAS E BIOLOGIA CELULAR (PT) 2016-08-04 US claimed
EP-3043782-A1 LIGHT-ACTIVATABLE POLYMERIC NANOPARTICLES Centro De Neurociéncias E Biologia Celular (PT) 2016-07-20 EP claimed
WO-2015036939-A1 LIGHT-ACTIVATABLE POLYMERIC NANOPARTICLES CNC - CENTRO DE NEUROCIÊNCIAS E BIOLOGIA CELULAR (PT) 2015-03-19 WO claimed
US-20140017169-A1 CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS BEN-GURION UNIVERSITY OF NEGEV RESEARCH & DEVELOPMENT AUTHORITY (IL) 2014-01-16 US claimed
EP-2575848-A2 CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS Ben-Gurion University of The Negev Research and Development Authority (IL) 2013-04-10 EP claimed
WO-2011151814-A2 CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) 2011-12-08 WO claimed
EP-1833987-A4 A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES YEDA RES & DEV (IL) 2009-03-11 EP claimed
EP-1833987-A2 A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES Yeda Research and Development Co. Ltd. at The Weizmann Institute of Science (IL) 2007-09-19 EP claimed
WO-2006064505-A2 A SINGLE-STEP PLATFORM FOR ON-CHIP INTEGRATION OF BIO-MOLECULES YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2006-06-22 WO claimed
CN-121569735-A Plant factory cultivation method for shortening rice growth period based on carbon-nitrogen nutrition regulation 中国农业科学院都市农业研究所 2026-02-27 CN disclosed
WO-1991016894-A1 QUINOLIZINONE TYPE COMPOUNDS ABBOTT LABORATORIES (US) 1991-11-14 WO disclosed
WO-1991007087-A1 SPATIALLY-ADDRESSABLE IMMOBILIZATION OF ANTI-LIGANDS ON SURFACES AFFYMAX TECHNOLOGIES N.V. (AN) 1991-05-30 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10167319-B2 Caged cell penetrating peptide-polymer conjugates for diagnostic and therapeutic applications PRCP, LNPEP, CLSPN ALDH1A1 4383/4885KDM4E 3603/4885SMN1; SMN2 3131/4885
US-20140017169-A1 CAGED CELL PENETRATING PEPTIDE-POLYMER CONJUGATES FOR DIAGNOSTIC AND THERAPEUTIC APPLICATIONS PRCP, LNPEP, CLSPN ALDH1A1 4383/4885KDM4E 3603/4885SMN1; SMN2 3131/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.