SCHEMBL7849103

SCHEMBL7849103

Cc1ccc(C)c(C(=O)c2ccccc2C(N)=O)c1

nearest known ligand 0.51

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.46
MEN1 O00255 3/20 0.45
KMT2A Q03164 3/20 0.45
KDM4E B2RXH2 3/20 0.45
ALDH1A1 P00352 6/20 0.44
MAPK1 P28482 1/20 0.43
POLB P06746 1/20 0.42
HPGD P15428 2/20 0.42
RAB9A P51151 2/20 0.42
AKR1C3 P42330 1/20 0.42
USP2 O75604 1/20 0.42
GAA P10253 1/20 0.42
LMNA P02545 1/20 0.42
TSHR P16473 1/20 0.42
HSD17B10 Q99714 1/20 0.42
PARP1 P09874 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7837115 0.86 NFE2L2 (0.46) NPSR1KMT2AKDM4EALDH1A1POLB
SCHEMBL11753699 0.85 TSHR (0.51) NPSR1MEN1KMT2AALDH1A1RAB9A
SCHEMBL7648043 0.84 AKR1C3 (0.61) NPSR1MEN1KMT2AALDH1A1POLB
SCHEMBL1003845 0.83 MEN1 (0.53) MEN1KMT2AKDM4EALDH1A1MAPK1
SCHEMBL9862051 0.83 MEN1 (0.57) MEN1KMT2AKDM4EALDH1A1MAPK1
SCHEMBL5962865 0.83 MAPT (0.51) MEN1KMT2AKDM4EALDH1A1MAPK1
Hydrochloric Acid SCHEMBL28266821 0.81 MEN1 (0.52) MEN1KMT2AKDM4EALDH1A1MAPK1
SCHEMBL7837520 0.81 ALDH1A1 (0.42) NPSR1MEN1KMT2AKDM4EALDH1A1
SCHEMBL9717031 0.79 ABCB1 (0.56) MEN1KMT2AKDM4EALDH1A1RAB9A
SCHEMBL11613043 0.77 KMT2A (0.45) NPSR1MEN1KMT2AMAPK1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US claimed
US-6328793-B1 FOR USE IN INK JET PRINTING PROCESSES, INCLUDING PIEZOELECTRIC INK JET PRINTING, ACOUSTIC INK JET PRINTING XEROX CORPORATION 2001-12-11 US disclosed