Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM2 | O94759 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | ENTPD1 | P49961 | 3/20 | 0.52 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.49 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.49 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.49 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.49 |
| ▸ | DTYMK | P23919 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7644549 | 0.88 | TRPM2 (0.65) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL30134675 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL12932270 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL1063721 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL7648504 | 0.86 | TRPM2 (0.64) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL2232893 | 0.83 | TRPM2 (0.61) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL15715797 | 0.82 | TRPM2 (0.60) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL15704019 | 0.82 | TRPM2 (0.60) | TRPM2POLBENTPD1ENPP1P2RY1 | |
| SCHEMBL5611431 | 0.82 | ADORA3 (0.59) | TRPM2 | |
| SCHEMBL5611437 | 0.82 | ADORA3 (0.59) | TRPM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7906490-B2 | Using vector transformation to generate transgenic cells expressing interfering RNA sequences; treatment and prevention of metabolic disorders | UNIVERSITY OF ROCHESTER (US) | 2011-03-15 | — | — | US | disclosed |
| US-20080227160-A1 | Circular DNA vectors for synthesis of RNA and DNA | UNIVERSITY OF ROCHESTER (US) | 2008-09-18 | — | — | US | disclosed |
| US-7135312-B2 | Circular DNA vectors for synthesis of RNA and DNA | UNIVERSITY OF ROCHESTER (US) | 2006-11-14 | — | — | US | disclosed |
| US-20030087241-A1 | Circular DNA vectors for synthesis of RNA and DNA | UNIVERSITY OF ROCHESTER (US) | 2003-05-08 | — | — | US | disclosed |
| US-6368802-B1 | A METHOD FOR SYNTHESIZING RNA OLIGONUCLEOTIDES BY MIXING A CIRCULAR SINGLE STRANDED TEMPLATE, WITH A NUCLEOTIDE SEQUENCE COMPLEMENTARY TO THE TARGET RNA OLIGONUCLEOTIDE, AND MIX WITH POLYMERASE ENZYME AND PRIMER TO CREATE RNA OLIGONUCLEOTIDES | UNIVERSITY OF ROCHESTER | 2002-04-09 | — | — | US | disclosed |
| US-6096880-A | BIOSYNTHESIS OF AN OLIGONUCLEOTIDE IN VITRO; COMBINING A SINGLE STRANDED NUCLEOTIDE SEQUENCE, TEMPLATE, RIBONUCLEOTIDE TRIPHOSPHATES AND POLYMERASE, RECOVER OLIGONUCLEOTIDE | UNIVERSITY OF ROCHESTER (US) | 2000-08-01 | — | — | US | disclosed |
| EP-1019535-A2 | HIGHLY SENSITIVE MULTIMERIC NUCLEIC ACID PROBES | THE UNIVERSITY OF ROCHESTER (US) | 2000-07-19 | — | — | EP | disclosed |
| US-6077668-A | OLIGONUCLEOTIDE OF 5' NONREPEATED REGION THAT BINDS A TARGET IN A SAMPLE FOLLOWED BY COPIES OF A REPEATED SEQUENCE WHICH INCLUDES AT LEAST ONE COPY OF A DETECTABLE LABEL; PRODUCED BY CONCURRENT SYNTHESIS AND LABEL INCORPORATION; FOR DIAGNOSIS | UNIVERSITY OF ROCHESTER (US) | 2000-06-20 | — | — | US | disclosed |
| EP-0977839-A1 | CIRCULAR DNA VECTORS FOR SYNTHESIS OF RNA AND DNA | University of Rochester (US) | 2000-02-09 | — | — | EP | disclosed |
| WO-1999009216-A9 | HIGHLY SENSITIVE MULTIMERIC NUCLEIC ACID PROBES | UNIV ROCHESTER (US) | 1999-08-05 | — | — | WO | disclosed |
| WO-1999009216-A2 | HIGHLY SENSITIVE MULTIMERIC NUCLEIC ACID PROBES | UNIVERSITY OF ROCHESTER (US) | 1999-02-25 | — | — | WO | disclosed |
| WO-1998038300-A1 | CIRCULAR DNA VECTORS FOR SYNTHESIS OF RNA AND DNA | UNIVERSITY OF ROCHESTER (US) | 1998-09-03 | — | — | WO | disclosed |
| US-5714320-A | ANNEALING OLIGONUCLEOTIDE PRIMER TO SINGLE-STRANDED CIRCULAR TEMPLATE, COMBINING WITH NUCLEOTIDE TRIPOLYPHOSPHATES AND POLYMERASE ENZYME TO YIELD SINGLE-STRANDED OLIGONUCLEOTIDE MULTIMER, CLEAVING | UNIVERSITY OF ROCHESTER (US) | 1998-02-03 | — | — | US | disclosed |