Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 9/20 | 0.47 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.46 |
| ▸ | INCENP | Q9NQS7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27738669 | 0.78 | MAPT (0.44) | ALDH1A1MEN1KMT2AGAASMN1; SMN2 | |
| SCHEMBL28153213 | 0.76 | KDM4E (0.53) | SYKAURKBINCENPALDH1A1KDM4E | |
| SCHEMBL10562958 | 0.74 | SCN8A (0.59) | SYKAURKBINCENPALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL8859896 | 0.73 | CYP2D6 (0.45) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL15701533 | 0.72 | MRGPRX4 (0.52) | SYKAURKBINCENPALDH1A1NPSR1 | |
| SCHEMBL9944264 | 0.71 | SYK (0.46) | SYKAURKBINCENPALDH1A1KDM4E | |
| SCHEMBL25003224 | 0.71 | GABRA1 (0.48) | SYKAURKBINCENPALDH1A1KDM4E | |
| SCHEMBL4564513 | 0.70 | CYP2D6 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL169753 | 0.70 | SMN1; SMN2 (0.63) | SYKAURKBINCENPALDH1A1GAA | |
| SCHEMBL13645800 | 0.70 | KDM4E (0.55) | SYKAURKBINCENPALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020065315-A1 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2002-05-30 | — | — | US | claimed |
| EP-1178963-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2002-02-13 | — | — | EP | claimed |
| WO-2000069823-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-11-23 | — | — | WO | claimed |
| US-20020065315-A1 | Ion channel modulating agents | POSEIDON PHARMACEUTICALS A/S (DK) | 2002-05-30 | — | — | US | disclosed |
| EP-1178963-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2002-02-13 | — | — | EP | disclosed |
| WO-2000069823-A1 | ION CHANNEL MODULATING AGENTS | NEUROSEARCH A/S (DK) | 2000-11-23 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020065315-A1 | Ion channel modulating agents | KCNN1, KCNN3, KCNN2 | SYK 1888/4885AURKB 1375/4885INCENP 3053/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.