Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.66 |
| ▸ | MPO | P05164 | 1/20 | 0.66 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | HTR2A | P28223 | 2/20 | 0.59 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | HTR1A | P08908 | 1/20 | 0.59 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.59 |
| ▸ | DRD2 | P14416 | 1/20 | 0.59 |
| ▸ | HPGD | P15428 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | HTR2C | P28335 | 1/20 | 0.59 |
| ▸ | ADRA1D | P25100 | 3/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11007868 | 0.89 | ADRA1D (0.61) | ALDH1A1KMT2AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL14306777 | 0.83 | ADRA1D (0.80) | KDM4ECYP2D6ADRA1D | |
| SCHEMBL2730275 | 0.81 | ALDH1A1 (1.00) | KDM4EALDH1A1KMT2AMPOSMN1; SMN2 | |
| SCHEMBL11047479 | 0.80 | ADRA1D (0.61) | HTR2ACYP2D6ADRA1D | |
| Hydrochloric Acid SCHEMBL2730111 | 0.80 | ALDH1A1 (0.97) | KDM4EALDH1A1KMT2AMPOSMN1; SMN2 | |
| SCHEMBL2732924 | 0.80 | KMT2A (1.00) | KDM4EALDH1A1KMT2AMPOSMN1; SMN2 | |
| SCHEMBL10740720 | 0.80 | CYP2D6 (0.53) | ALDH1A1KMT2AHTR2ACYP2D6CYP1A2 | |
| SCHEMBL10744006 | 0.80 | SLC6A4 (0.53) | CYP2D6HTR1ADRD2ADRA1D | |
| SCHEMBL11013197 | 0.80 | DRD2 (0.61) | KDM4EALDH1A1KMT2AHTR2ACYP2D6 | |
| SCHEMBL15613370 | 0.79 | KDM4E (0.81) | KDM4EALDH1A1KMT2AMPOSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6492364-B1 | Triazolo and derivatives as chemokine inhibitors | TORAY INDUSTRIES, INC. (JP) | 2002-12-10 | — | — | US | disclosed |
| EP-1067130-A1 | TRIAZOLO DERIVATIVES AND CHEMOKINE INHIBITORS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | TORAY INDUSTRIES, INC. (JP) | 2001-01-10 | — | — | EP | disclosed |