Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.43 |
| ▸ | DNMT3B | Q9UBC3 | 1/20 | 0.43 |
| ▸ | DNMT3L | Q9UJW3 | 1/20 | 0.43 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.40 |
| ▸ | HNF4A | P41235 | 1/20 | 0.39 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13302505 | 0.78 | KLKB1 (0.68) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL21035765 | 0.78 | LCK (0.61) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL925372 | 0.77 | TRPA1 (0.57) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL8568065 | 0.77 | MAOA (0.50) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL11337098 | 0.75 | MAOA (0.53) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL21632307 | 0.75 | PLG (0.49) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL312283 | 0.75 | MAOA (0.49) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL8569507 | 0.75 | MAOA (0.46) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL8565952 | 0.75 | MAOA (0.46) | MAOBMAOAKLKB1CTSBMMP9 | |
| SCHEMBL31536497 | 0.75 | PPARA (0.50) | MAOBKLKB1CTSBMMP9DNMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479671-B1 | Process for producing optically active chromene derivative | SHIONOGI & CO., LTD. (JP) | 2002-11-12 | — | — | US | disclosed |
| US-6218427-B1 | AS ENDOTHELIN RECEPTOR ANTAGONIST | SHIONOGI & CO., LTD. (JP) | 2001-04-17 | — | — | US | disclosed |
| EP-1057824-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE CHROMENE DERIVATIVE | SHIONOGI & CO., LTD. (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0924207-A1 | CHROMENE-3-CARBOXYLATE DERIVATIVES | SHIONOGI & CO., LTD. (JP) | 1999-06-23 | — | — | EP | disclosed |