Methionine

Methionine

SCHEMBL7649643

CSCC[C@H](N)C(=O)O.C[C@@H](OC(=O)[C@@H](N)CS)[C@H](N)C(=O)OC[C@H](N)C(=O)O

nearest known ligand 0.51

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Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
BHMT Q93088 6/20 0.37
BHMT2 Q9H2M3 1/20 0.37
PTGS1 P23219 1/20 0.36
SLC7A11 Q9UPY5 1/20 0.36
FNTA P49354 6/20 0.35
FNTB P49356 6/20 0.35
PGGT1B P53609 4/20 0.35
RNPEP Q9H4A4 1/20 0.35
ANPEP P15144 1/20 0.33
ENPEP Q07075 1/20 0.33
NOS2 P35228 2/20 0.32
NOS3 P29474 1/20 0.32
NOS1 P29475 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methionine SCHEMBL7343873 0.93 BHMT (0.34) BHMTBHMT2PTGS1SLC7A11FNTA
SCHEMBL2551500 0.91 BHMT (0.38) BHMTBHMT2RNPEPNOS2NOS3
Glutamine SCHEMBL5957029 0.90 ALOX15 (0.37) BHMTBHMT2FNTAFNTBPGGT1B
SCHEMBL6389078 0.88 PTGS1 (0.46) PTGS1SLC7A11ENPEPNOS2NOS3
Glycine SCHEMBL6361607 0.86 BHMT (0.36) BHMTBHMT2RNPEPNOS2NOS3
SCHEMBL1579771 0.79 RNPEP (0.41) BHMTBHMT2RNPEPNOS2NOS3
SCHEMBL3995873 0.78 METAP2 (0.32)
SCHEMBL2260606 0.77 RNPEP (0.44) BHMTBHMT2RNPEPNOS2NOS3
Racemethionine SCHEMBL23924425 0.77 PTGS1 (0.61) BHMTBHMT2PTGS1SLC7A11FNTA
Methionine SCHEMBL4623092 0.77 PTGS1 (0.61) BHMTBHMT2PTGS1SLC7A11FNTA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2002013773-A2 COSMETIC COMPOSITION UNILEVER PLC (GB) 2002-02-21 WO disclosed
EP-0873304-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1998-10-28 EP disclosed
WO-1997019053-A1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARMACEUTICALS LIMITED (GB) 1997-05-29 WO disclosed