Glutamine

Glutamine

SCHEMBL5957029

CSCC[C@H](N)C(=O)O.C[C@@H](OC(=O)[C@@H](N)CS)[C@H](N)C(=O)OC[C@H](N)C(=O)O.NC(=O)CC[C@H](N)C(=O)O.NC(=O)C[C@H](N)C(=O)O

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.37
BLM P54132 1/20 0.37
PMP22 Q01453 1/20 0.37
KMT2A Q03164 1/20 0.37
FNTA P49354 2/20 0.32
FNTB P49356 2/20 0.32
PGGT1B P53609 1/20 0.32
BHMT Q93088 3/20 0.32
BHMT2 Q9H2M3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methionine SCHEMBL7343873 0.96 BHMT (0.34) FNTAFNTBPGGT1BBHMTBHMT2
Methionine SCHEMBL7649643 0.90 BHMT (0.37) FNTAFNTBPGGT1BBHMTBHMT2
SCHEMBL2551500 0.82 BHMT (0.38) BHMTBHMT2
SCHEMBL6389078 0.79 PTGS1 (0.46)
Glutamine SCHEMBL28402739 0.79 GSR (0.36) ALOX15BLMPMP22KMT2AFNTA
SCHEMBL8695381 0.78 NOS3 (0.38) ALOX15BLMPMP22KMT2A
Glycine SCHEMBL6361607 0.78 BHMT (0.36) BHMTBHMT2
Asparagine SCHEMBL6130108 0.76 ALOX15 (0.50) ALOX15BLMPMP22KMT2A
Glutamine SCHEMBL5957032 0.76 ALOX15 (0.40) ALOX15BLMPMP22KMT2AFNTA
Glutamine SCHEMBL1900122 0.75 SLC7A5 (0.37) ALOX15BLMPMP22KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3904528-A1 DP04 POLYMERASE VARIANTS Stratos Genomics Inc. (US) 2021-11-03 EP disclosed
EP-3056575-A1 POLYMERASES FOR NUCLEOTIDE ANALOGUE INCORPORATION Pacific Biosciences Of California, Inc. (US) 2016-08-17 EP disclosed
CN-101365807-A Polymerases for incorporation of nucleotide analogs PACIFIC BIOSCIENCES CALIFORNIA (US) 2009-02-11 CN disclosed
EP-1666604-A1 Compositions of orthogonal lysyl-tRNA and aminoacyl-tRNA synthetase pairs and uses thereof The Scripps Research Institute (US) 2006-06-07 EP disclosed