Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7648460 | 0.84 | C3AR1 (0.53) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7648470 | 0.84 | C3AR1 (0.53) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7652741 | 0.80 | C3AR1 (0.44) | POLBMEN1KMT2AMAPTSMN1; SMN2 | |
| SCHEMBL7649508 | 0.77 | KMT2A (0.54) | POLBMEN1KMT2AC3AR1TDP1 | |
| SCHEMBL7651910 | 0.77 | KMT2A (0.54) | POLBMEN1KMT2AC3AR1TDP1 | |
| SCHEMBL7860325 | 0.77 | C3AR1 (0.45) | KMT2AC3AR1 | |
| SCHEMBL7653534 | 0.76 | GPR34 (0.57) | MEN1KMT2AMAPTC3AR1 | |
| SCHEMBL1568736 | 0.75 | C3AR1 (0.83) | C3AR1 | |
| SCHEMBL1568729 | 0.75 | C3AR1 (0.83) | C3AR1 | |
| Benzene SCHEMBL6278673 | 0.73 | C3AR1 (0.49) | C3AR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | claimed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | claimed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | claimed |
| US-6489339-B1 | C3A receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2002-12-03 | — | — | US | disclosed |
| EP-1119357-A1 | C3A RECEPTOR LIGANDS | SmithKline Beecham Corporation (US) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000009129-A1 | C3A RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-02-24 | — | — | WO | disclosed |