Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | TACR1 | P25103 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6804827 | 0.81 | HPGD (0.43) | HPGDALDH1A1KDM4EKCNA3CHRM1 | |
| SCHEMBL8519689 | 0.73 | HPGD (0.41) | HPGDALDH1A1KDM4ECHRM1TSHR | |
| SCHEMBL6799229 | 0.73 | HPGD (0.41) | HPGDALDH1A1KDM4ECHRM1TSHR | |
| SCHEMBL6803688 | 0.70 | HPGD (0.38) | HPGDALDH1A1LMNAL3MBTL1 | |
| SCHEMBL6803235 | 0.67 | HDAC3 (0.37) | HPGDALDH1A1KDM4E | |
| SCHEMBL27497020 | 0.65 | L3MBTL1 (0.39) | HPGDALDH1A1KDM4ELMNAPOLB | |
| SCHEMBL27560649 | 0.65 | SMN1; SMN2 (0.59) | HPGDKCNA3SMN1; SMN2TSHRNPC1 | |
| SCHEMBL4768337 | 0.64 | MMP8 (0.48) | ALDH1A1KDM4ESMN1; SMN2TSHRLMNA | |
| SCHEMBL5370889 | 0.64 | MTNR1A (0.54) | — | |
| SCHEMBL20487157 | 0.63 | TSHR (0.53) | HPGDALDH1A1CHRM1SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6462023-B1 | SUCH AS 2-HYDROXY-HYDROXYCARBAMOYL-METHYL)-4-METHYL-PENTANOYLAMINE)-2-PHENYL -ETHANOIC ACID CYCLOPENTYL ESTER; INHIBITING HYPERPROLIFERATIVE TUMOURGENIC CELLS SUCH AS MELANOMA AND/OR LYMPHOMA CELLS | BRITISH BIOTECH PHARMACEUTICALS, LTD. (GB) | 2002-10-08 | — | — | US | disclosed |