SCHEMBL764986

SCHEMBL764986

Fc1c(F)c(F)c(N2COc3cccnc3C2)c(F)c1F

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 1/20 0.32
PDE3A Q14432 1/20 0.32
TIPARP Q7Z3E1 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8994631 0.92
SCHEMBL13243223 0.83
SCHEMBL10311126 0.81 MAPT (0.37) PDE3BPDE3ATIPARP
SCHEMBL10311131 0.80 CHKA (0.38) PDE3BPDE3ATIPARP
SCHEMBL10311137 0.78 MAPT (0.42) PDE3BPDE3ATIPARP
SCHEMBL764340 0.77 KAT2B (0.38)
SCHEMBL10311119 0.77 GRIN2D (0.43)
SCHEMBL10311130 0.75 CHRNB2 (0.41)
SCHEMBL765507 0.72
SCHEMBL20281108 0.64 DRD2 (0.37)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9006300-B2 Method for mechanically stabilizing nitrogen-containing polymers SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-04-14 US disclosed
US-9006300-B2 Method for mechanically stabilizing nitrogen-containing polymers SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-04-14 US disclosed
US-8507148-B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-08-13 US disclosed
US-8507148-B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2013-08-13 US disclosed
US-20120251920-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-04 US disclosed
US-20120251920-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-10-04 US disclosed
US-20120231365-A1 METHOD FOR MECHANICALLY STABILIZING NITROGEN-CONTAINING POLYMERS SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-09-13 US disclosed
US-20120231365-A1 METHOD FOR MECHANICALLY STABILIZING NITROGEN-CONTAINING POLYMERS SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-09-13 US disclosed
US-8187766-B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-29 US disclosed
US-8187766-B2 Benzoxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2012-05-29 US disclosed
EP-2221302-B1 Pyrido-oxazine-based monomer, polymer thereof, electrode for fuel cell including the polymer, electrolyte membrane for fuel cell including the polymer, and fuel cell using the electrode SAMSUNG ELECTRONICS CO LTD (KR) 2012-03-21 EP disclosed
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-07 US disclosed
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2009-05-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090117440-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE HCN1, PXMP4, GJA1 PDE3B 4016/4885PDE3A 3614/4885TIPARP 4406/4885
US-20120251920-A1 BENZOXAZINE-BASED MONOMER, POLYMER THEREOF, ELECTRODE FOR FUEL CELL INCLUDING THE POLYMER, ELECTROLYTE MEMBRANE FOR FUEL CELL INCLUDING THE POLYMER, AND FUEL CELL USING THE ELECTRODE HCN1, PXMP4, GJA1 PDE3B 4016/4885PDE3A 3614/4885TIPARP 4406/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.