Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.41 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.40 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARD | Q03181 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL127434 | 0.86 | CYP3A4 (0.47) | SMN1; SMN2ALDH1A1LMNAACACBPPARG | |
| SCHEMBL9614864 | 0.80 | SMN1; SMN2 (0.48) | LTA4HSMN1; SMN2ALDH1A1LMNAESR1 | |
| SCHEMBL7764968 | 0.80 | CYP3A4 (0.45) | SMN1; SMN2ALDH1A1LMNAACACBPPARG | |
| SCHEMBL30125294 | 0.80 | BLM (0.59) | LTA4HSMN1; SMN2ALDH1A1LMNAACACB | |
| SCHEMBL5560855 | 0.80 | PPARA (0.41) | ALDH1A1LMNAACACBPPARA | |
| SCHEMBL8385819 | 0.79 | ALDH1A1 (0.39) | SMN1; SMN2ALDH1A1LMNAACACBPPARG | |
| SCHEMBL3680771 | 0.77 | PPARD (0.40) | LTA4HALDH1A1LMNAACACBPPARG | |
| SCHEMBL196997 | 0.77 | THRB (0.57) | SMN1; SMN2ALDH1A1LMNAACACBPPARG | |
| SCHEMBL6562700 | 0.77 | POLB (0.50) | ALDH1A1LMNAACACBPPARGPPARD | |
| SCHEMBL3677849 | 0.77 | LMNA (0.40) | LTA4HALDH1A1LMNAACACBPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495011-A4 | HYDROPHILIC POLYURETHANE ELASTOMERS | — | 1992-08-12 | — | — | EP | claimed |
| EP-0495011-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | PolyMedica Industries, Inc. (US) | 1992-07-22 | — | — | EP | claimed |
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | claimed |
| WO-1991005809-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | POLYMEDICA INDUSTRIES, INC. (US) | 1991-05-02 | — | — | WO | claimed |
| US-6475663-B1 | Compositions suitable for electrochemical cells | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-05 | — | — | US | disclosed |
| EP-0495011-A4 | HYDROPHILIC POLYURETHANE ELASTOMERS | — | 1992-08-12 | — | — | EP | disclosed |
| EP-0495011-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | PolyMedica Industries, Inc. (US) | 1992-07-22 | — | — | EP | disclosed |
| US-5118779-A | Drug delivery | POLYMEDICA INDUSTRIES, INC. (US) | 1992-06-02 | — | — | US | disclosed |
| WO-1991005809-A1 | HYDROPHILIC POLYURETHANE ELASTOMERS | POLYMEDICA INDUSTRIES, INC. (US) | 1991-05-02 | — | — | WO | disclosed |