Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARG | Q86W56 | 2/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.44 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6256616 | 0.90 | MMP13 (0.59) | PARGMMP13SLC22A8DPP4MAPT | |
| SCHEMBL6256249 | 0.88 | MMP13 (0.61) | PARGMMP13SLC22A8MEN1MAPT | |
| SCHEMBL7660107 | 0.87 | PARG (0.48) | PARGMMP13SLC22A8DPP4HDAC1 | |
| SCHEMBL7018313 | 0.85 | MMP13 (0.59) | MMP13SLC22A8DPP4MAPTHDAC1 | |
| SCHEMBL7020566 | 0.83 | MAPT (0.54) | MMP13MEN1MAPTTSHRKMT2A | |
| SCHEMBL7103213 | 0.81 | PARG (0.52) | PARGMMP13SLC22A8MEN1KMT2A | |
| SCHEMBL7634243 | 0.81 | TP53 (0.57) | PARGMMP13SLC22A8MAPTHDAC1 | |
| SCHEMBL6259580 | 0.80 | MMP13 (0.61) | MMP13SLC22A8MEN1MAPTKMT2A | |
| SCHEMBL7105028 | 0.80 | MMP13 (0.59) | PARGMMP13SLC22A8MAPTHDAC1 | |
| SCHEMBL5696996 | 0.79 | MMP13 (0.55) | PARGMMP13SLC22A8DPP4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | ANDRIANJARA CHARLES (FR) | 2002-12-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020193377-A1 | Quinazolines as MMP-13 inhibitors | MMP13, MMP9, MMP3 | PARG 3624/4885MMP13 1/4885SLC22A8 315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.