Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | STAT1 | P42224 | 1/20 | 0.41 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.40 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.40 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301593 | 0.91 | HDAC1 (0.54) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6301341 | 0.89 | KMT2A (0.48) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6301558 | 0.89 | KMT2A (0.48) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6301182 | 0.89 | KMT2A (0.47) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6301145 | 0.88 | KMT2A (0.47) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6430006 | 0.88 | KMT2A (0.47) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6303883 | 0.87 | RAB9A (0.59) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL7657052 | 0.86 | KMT2A (0.58) | ALDH1A1KMT2ARAB9AKDM4EPOLB | |
| SCHEMBL6301413 | 0.86 | KMT2A (0.45) | ALDH1A1KMT2ARAB9ACYP1A2HDAC1 | |
| SCHEMBL6307818 | 0.83 | ALOX15 (0.45) | KMT2ARAB9ACYP1A2ALOX15POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6420409-B1 | GLUCOSE TOLERANCE, DIABETES,INSULIN RESISTANCE, POLYCYSTIC OVARY SYNDROME, HYPERLIPIDEMIA, ATHEROSCLEROSIS, CARDIOVASCULAR DISORDERS, HYPERGLYCEMIA, HYPERTENSION, STENOCARDIA, PULMONARY HYPERTENSION, CONGESTIVE HEART FAILURE, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1020452-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |