Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CETP | P11597 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650334 | 0.88 | ALDH1A1 (0.55) | KMT2ACYP1A2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6301593 | 0.88 | HDAC1 (0.54) | KMT2ACYP1A2RAB9AMEN1ALDH1A1 | |
| SCHEMBL6301341 | 0.86 | KMT2A (0.48) | KMT2ACYP1A2RAB9AALDH1A1L3MBTL1 | |
| SCHEMBL6301558 | 0.86 | KMT2A (0.48) | KMT2ACYP1A2RAB9AMEN1ALDH1A1 | |
| SCHEMBL6301182 | 0.85 | KMT2A (0.47) | KMT2ACYP1A2RAB9AMEN1ALDH1A1 | |
| SCHEMBL6301145 | 0.84 | KMT2A (0.47) | KMT2ACYP1A2RAB9AMEN1ALDH1A1 | |
| SCHEMBL6303883 | 0.83 | RAB9A (0.59) | KMT2ACYP1A2RAB9AALDH1A1HDAC1 | |
| SCHEMBL7657052 | 0.82 | KMT2A (0.58) | KMT2ARAB9AMEN1ALDH1A1POLB | |
| SCHEMBL6301413 | 0.82 | KMT2A (0.45) | KMT2ACYP1A2RAB9AMEN1ALDH1A1 | |
| SCHEMBL6307818 | 0.79 | ALOX15 (0.45) | KMT2ACYP1A2RAB9AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6869950-B1 | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-03-22 | — | — | US | disclosed |
| US-20050014955-A1 | Process for the preapartion 3-aryl-2-hydroxypropionic acid derivative | ASTRAZENECA AB (SE) | 2005-01-20 | — | — | US | disclosed |
| CN-1135224-C | Benzimidazole derivatives | ����ҩƷ��ҵ��ʽ���� | 2004-01-21 | — | — | CN | disclosed |
| US-6420409-B1 | GLUCOSE TOLERANCE, DIABETES,INSULIN RESISTANCE, POLYCYSTIC OVARY SYNDROME, HYPERLIPIDEMIA, ATHEROSCLEROSIS, CARDIOVASCULAR DISORDERS, HYPERGLYCEMIA, HYPERTENSION, STENOCARDIA, PULMONARY HYPERTENSION, CONGESTIVE HEART FAILURE, | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-07-16 | — | — | US | disclosed |
| EP-1142880-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| CN-1268123-A | Benzimidazole derivatives | FUJISAWA PHARMACEUTICAL CO (JP) | 2000-09-27 | — | — | CN | disclosed |
| EP-1020452-A1 | BENZIMIDAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050014955-A1 | Process for the preapartion 3-aryl-2-hydroxypropionic acid derivative | GRHPR, PAH, P4HA1 | KMT2A 2044/4885CYP1A2 15/4885CYP2C9 46/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.