SCHEMBL7650488

SCHEMBL7650488

Brc1ccccc1[Si](c1ccccc1)(c1ccccc1)c1ccccc1

nearest known ligand 0.37

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.37
MAPK1 P28482 3/20 0.37
TDP1 Q9NUW8 1/20 0.35
RAB9A P51151 2/20 0.33
TP53 P04637 1/20 0.33
MAPT P10636 1/20 0.33
NFKB1 P19838 1/20 0.33
NFKB2 Q00653 1/20 0.33
RELA Q04206 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
NR1H2 P55055 1/20 0.32
NR1H3 Q13133 1/20 0.32
PBRM1 Q86U86 1/20 0.32
BBOX1 O75936 1/20 0.31
EHMT2 Q96KQ7 1/20 0.31
EHMT1 Q9H9B1 1/20 0.31
NPC1 O15118 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28362548 0.95 ALDH1A1 (0.37) ALDH1A1MAPK1TDP1BBOX1EHMT2
SCHEMBL103831 0.81 NPC1 (0.38) ALDH1A1MAPK1TDP1RAB9AMAPT
SCHEMBL6931675 0.78 ALDH1A1 (0.36) ALDH1A1MAPK1TDP1
SCHEMBL30030347 0.76 ALDH1A1 (0.34) ALDH1A1MAPK1TDP1
SCHEMBL2586783 0.76 ALDH1A1 (0.34) ALDH1A1MAPK1TDP1
SCHEMBL15858820 0.76 ESR1 (0.45) ALDH1A1MAPK1TDP1RAB9ATP53
SCHEMBL31643462 0.74 GRIK1 (0.36) ALDH1A1MAPK1TDP1RAB9ATP53
SCHEMBL28752013 0.74 ALDH1A1 (0.41) ALDH1A1MAPK1RAB9AMAPTNFKB1
SCHEMBL13295274 0.74 NPC1 (0.33) ALDH1A1MAPK1RAB9AMAPTL3MBTL1
SCHEMBL28595147 0.73 TDP1 (0.32) TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110540545-B Organic electroluminescent device and monoamine compound for organic electroluminescent device 三星显示有限公司 2024-04-09 CN disclosed
CN-110540545-A Organic electroluminescent device and monoamine compound for organic electroluminescent device SAMSUNG DISPLAY CO LTD 2019-12-06 CN disclosed
CN-110128460-A A kind of siliceous electroluminescent organic material and preparation method thereof 黑龙江省科学院石油化学研究院 2019-08-16 CN disclosed
US-6338909-B1 UNSATURATED AROMATIC LIGHT EMITTERS FOR DYE DEVELOPMENT SAMSUNG DISPLAY DEVICES CO., LTD. (KR) 2002-01-15 US disclosed