SCHEMBL28595147

SCHEMBL28595147

Brc1cc([Si](c2ccccc2)(c2ccccc2)c2ccccc2)c(Br)c(Br)c1Br

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 1/20 0.32
NQO2 P16083 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4572772 0.75 CRHBP (0.42)
SCHEMBL7650488 0.73 ALDH1A1 (0.37) TDP1
SCHEMBL103831 0.69 NPC1 (0.38) TDP1
SCHEMBL28362548 0.69 ALDH1A1 (0.37) TDP1
SCHEMBL28752013 0.68 ALDH1A1 (0.41)
SCHEMBL31643462 0.68 GRIK1 (0.36) TDP1
SCHEMBL19588509 0.67 CYP2A6 (0.37) TDP1NQO2
SCHEMBL464991 0.65 ALDH1A1 (0.40) TDP1
SCHEMBL28864155 0.64 ALDH1A1 (0.43)
SCHEMBL4572757 0.64 ALDH1A1 (0.41) TDP1NQO2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113101899-B Organic aryne doped porous aromatic skeleton composite material and preparation method and application thereof 东北师范大学 2022-04-15 CN disclosed
CN-113101899-A Organic aryne doped porous aromatic skeleton composite material and preparation method and application thereof 东北师范大学 2021-07-13 CN disclosed