Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.50 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | EDNRB | P24530 | 2/20 | 0.44 |
| ▸ | EDNRA | P25101 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MC4R | P32245 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7663095 | 0.88 | CHEK2 (0.53) | ALDH1A1MAPK1ALOX5KDM4EHPGD | |
| SCHEMBL7652598 | 0.84 | UCHL1 (0.48) | MAPK1ALOX5KMT2AMEN1GAA | |
| SCHEMBL7652092 | 0.80 | ALDH1A1 (0.50) | ALDH1A1MAPK1SRD5A2TP53DHODH | |
| SCHEMBL27660779 | 0.77 | ALDH1A1 (0.53) | ALDH1A1MAPK1SRD5A2TP53DHODH | |
| SCHEMBL6535581 | 0.77 | ALDH1A1 (0.70) | ALDH1A1MAPK1SRD5A2TP53DHODH | |
| SCHEMBL12209749 | 0.76 | ALDH1A1 (0.50) | ALDH1A1MAPK1ALOX5SRD5A2TP53 | |
| SCHEMBL2945422 | 0.76 | ALDH1A1 (0.73) | ALDH1A1MAPK1ALOX5SRD5A2CTNNB1 | |
| SCHEMBL2957088 | 0.75 | P2RY14 (0.53) | ALDH1A1ALOX5PKMKMT2AEDNRB | |
| SCHEMBL5989554 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MAPK1SRD5A2TP53KDM4E | |
| SCHEMBL2496476 | 0.71 | ALDH1A1 (0.57) | ALDH1A1MAPK1SRD5A2TP53DHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |