Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 7/20 | 0.44 |
| ▸ | ADORA1 | P30542 | 6/20 | 0.44 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.44 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7650593 | 0.84 | ALDH1A1 (0.54) | ALOX5MEN1KMT2AGAAMAPK1 | |
| SCHEMBL7663095 | 0.83 | CHEK2 (0.53) | ALOX5CYP1A2CYP3A4CYP2D6TSHR | |
| SCHEMBL7657293 | 0.82 | UCHL1 (0.46) | UCHL1USP30MEN1KMT2ALMNA | |
| SCHEMBL5192592 | 0.75 | KMT2A (0.70) | MEN1KMT2ALMNAGAAMAPK1 | |
| SCHEMBL7662370 | 0.74 | ALOX5 (0.65) | ALOX5MEN1KMT2AGAAADORA3 | |
| SCHEMBL19391079 | 0.70 | CD274 (0.56) | ALOX5MEN1KMT2ATSHR | |
| SCHEMBL7662426 | 0.69 | ADORA3 (0.43) | MEN1KMT2AGAAADORA3ADORA1 | |
| SCHEMBL7659381 | 0.67 | KDM4E (0.49) | MEN1KMT2ALMNATSHRMAPK1 | |
| SCHEMBL13971739 | 0.67 | MAPT (0.62) | MEN1KMT2ALMNAADORA3ADORA1 | |
| SCHEMBL30300419 | 0.66 | RAB9A (0.50) | MEN1KMT2ATSHRHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340704-B1 | TREATING NERVE DISEASE OR BONE/JOINT DISEASE | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-01-22 | — | — | US | disclosed |