Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | S100A4 | P26447 | 2/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | HTR2A | P28223 | 1/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
| ▸ | HTR2B | P41595 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7509156 | 0.81 | RPS6KA3 (0.35) | ALDH1A1LMNAHSD11B1 | |
| SCHEMBL7510824 | 0.80 | MAPT (0.31) | LMNAMAPT | |
| SCHEMBL7510124 | 0.78 | L3MBTL1 (0.40) | ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7887336 | 0.73 | MAPT (0.34) | MAPT | |
| SCHEMBL7749240 | 0.71 | ESPL1 (0.30) | — | |
| SCHEMBL7711809 | 0.71 | L3MBTL1 (0.41) | ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7891112 | 0.70 | F2 (0.31) | — | |
| SCHEMBL8892234 | 0.70 | MAPT (0.38) | ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7707619 | 0.70 | CFTR (0.39) | ALDH1A1LMNAPOLBMAPT | |
| SCHEMBL7505658 | 0.70 | HSD11B1 (0.34) | HSD11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482774-B1 | Substituted (4-brompyrazole-3-yl) benzazoles | BASF AKTIENGESELLSCHAFT (DE) | 2002-11-19 | — | — | US | disclosed |
| CN-1302298-A | Substituted (4-brompyrazole-3-yl) indole | BASF AG (DE) | 2001-07-04 | — | — | CN | disclosed |