Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7649700 | 0.91 | LMNA (0.59) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7646475 | 0.89 | LMNA (0.50) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7649894 | 0.82 | MEN1 (0.49) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7649479 | 0.81 | SIGMAR1 (0.47) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7653388 | 0.81 | RAD52 (0.39) | MEN1KMT2AOPRD1 | |
| SCHEMBL7652383 | 0.80 | LMNA (0.50) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7649914 | 0.80 | IGF1R (0.47) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7653466 | 0.80 | LMNA (0.65) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7650378 | 0.78 | MEN1 (0.43) | LMNAGAAKDM4EMEN1KMT2A | |
| SCHEMBL7649923 | 0.77 | ALDH1A1 (0.49) | LMNAKDM4EMEN1KMT2AMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1237887-A1 | 9-(PIPERAZINYLALKYL)CARBAZOLES AS BAX-MODULATORS | Applied Research Systems ARS Holding N.V. (AN) | 2002-09-11 | — | — | EP | disclosed |
| WO-2001029028-A1 | 9- (PIPERAZINYLALKYL) CARBAZOLES AS BAX-MODULATORS | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2001-04-26 | — | — | WO | disclosed |