Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.42 |
| ▸ | TSHR | P16473 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 3/20 | 0.40 |
| ▸ | CA2 | P00918 | 3/20 | 0.40 |
| ▸ | CA9 | Q16790 | 3/20 | 0.40 |
| ▸ | CA5A | P35218 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | CFTR | P13569 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL679492 | 0.84 | TSHR (0.50) | MAPTALDH1A1TSHRCA1CA2 | |
| SCHEMBL826320 | 0.82 | MAPT (0.60) | MAPTHDAC8ALDH1A1TSHRCA1 | |
| SCHEMBL29074431 | 0.82 | MAPT (0.60) | MAPTHDAC8ALDH1A1TSHRCA1 | |
| SCHEMBL28479127 | 0.79 | MAPT (0.52) | MAPTHDAC8ALDH1A1TSHRCA1 | |
| SCHEMBL28230005 | 0.78 | MAPT (0.56) | MAPTHDAC8ALDH1A1TSHRCA1 | |
| SCHEMBL212175 | 0.78 | TSHR (0.61) | MAPTHDAC8ALDH1A1TSHRCA1 | |
| SCHEMBL24683903 | 0.77 | BCAT2 (0.43) | MAPTALDH1A1TSHRHSD17B10CFTR | |
| SCHEMBL29057700 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1TSHRCA2HSD17B10 | |
| SCHEMBL31167438 | 0.77 | ALDH1A1 (0.47) | MAPTALDH1A1TSHRCA2HSD17B10 | |
| SCHEMBL574618 | 0.76 | TSHR (0.63) | MAPTALDH1A1TSHRCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | claimed |
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | SIEMENS AKTIENGESELLSCHAFT | 2001-12-27 | — | — | US | claimed |
| EP-0905124-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| EP-0905123-B1 | o-amino(thio)phenol-carboxylic acids and their preparation | INFINEON TECHNOLOGIES AG (DE) | 2001-12-12 | — | — | EP | claimed |
| US-6310238-B1 | INTERMEDIATES FOR THE PREPARATION OF POLYBENZOXAZOLES AND POLYBENZOTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2001-10-30 | — | — | US | claimed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | claimed |
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | claimed |
| JP-11171995-A | — | — | None | — | — | JP | disclosed |
| JP-11158129-A | — | — | None | — | — | JP | disclosed |
| JP-11158128-A | — | — | None | — | — | JP | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-6437178-B2 | REACTING A HALOGENATED BENZENE COMPOUND WITH NITRO(THIO)PHENOL; REDUCTION | INFINEON TECHNOLOGIES AG (DE) | 2002-08-20 | — | — | US | disclosed |
| US-6120970-A | Polybenzoxazole and polybenzothiazole precursors | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-09-19 | — | — | US | disclosed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-6096921-A | USED FOR THE PREPARATION OF HIGH-TEMPERATURE-STABLE POLYMERS, SUCH AS POLYBENZOXAZOLES AND POLYBENZTHIAZOLES | SIEMENS AKTIENGESELLSCHAFT (DE) | 2000-08-01 | — | — | US | disclosed |
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| US-5998662-A | O-amino (thio) phenolcarboxylic acids and their preparation | SIEMENS AKTIENGESELLSCHAFT (DE) | 1999-12-07 | — | — | US | disclosed |
| JP-H11158128-A | O-AMINO(THIO)PHENOL CARBOXYLIC ACID AND ITS PRODUCTION | SIEMENS AG | 1999-06-15 | — | — | JP | disclosed |
| JP-H11158129-A | BIS-O-AMINO(THIO)PHENOL ACID AND ITS PRODUCTION | SIEMENS AG | 1999-06-15 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010056203-A1 | O-aminophenolcarboxylic acid and o-aminothiophenolcarboxylic acid | TPMT, PAH, AADAT | MAPT 3652/4885HDAC8 1918/4885ALDH1A1 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.