Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.63 |
| ▸ | LMNA | P02545 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 7/20 | 0.59 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.59 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.54 |
| ▸ | CA9 | Q16790 | 2/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.54 |
| ▸ | CA2 | P00918 | 1/20 | 0.54 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.54 |
| ▸ | CA4 | P22748 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.54 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28540211 | 0.98 | TSHR (0.61) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| Water SCHEMBL19915275 | 0.98 | TSHR (0.61) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL734992 | 0.98 | TSHR (0.61) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL734993 | 0.98 | TSHR (0.61) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL679492 | 0.85 | TSHR (0.50) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL16598169 | 0.82 | LMNA (0.63) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL10203414 | 0.81 | LMNA (0.68) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL3908136 | 0.81 | LMNA (0.68) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| SCHEMBL29525350 | 0.81 | LMNA (0.68) | TSHRLMNAHPGDHSD17B10ALOX15 | |
| Salicylic Acid SCHEMBL8206603 | 0.80 | ALDH1A1 (0.58) | TSHRLMNAHPGDHSD17B10ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 335 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4013420-B1 | METHOD OF BLOCKING OR AMELIORATING CYTOKINE RELEASE SYNDROME | RIGEL PHARMACEUTICALS INC (US) | 2023-11-01 | — | — | EP | claimed |
| EP-4054524-A1 | COMPOSITIONS OF CLOFAZIMINE, COMBINATIONS COMPRISING THEM, PROCESSES FOR THEIR PREPARATION, USES AND METHODS OF TREATMENT COMPRISING THEM | MannKind Corporation (US) | 2022-09-14 | — | — | EP | claimed |
| CN-111470796-B | Cement grinding aid | 辽宁天宝华瑞建材有限公司 | 2022-03-15 | — | — | CN | claimed |
| US-20210246187-A1 | BTNL3/8 TARGETING CONSTRUCTS FOR DELIVERY OF PAYLOADS TO THE GASTROINTESTINAL SYSTEM | KING'S COLLEGE LONDON (GB) | 2021-08-12 | — | — | US | claimed |
| CN-111470796-A | Cement grinding aid | 辽宁天宝华瑞建材有限公司 | 2020-07-31 | — | — | CN | claimed |
| CN-109970137-A | A method of the hyperbranched magnetic material rich in functional group removes heavy-metal composite pollution object | 天津工业大学 | 2019-07-05 | — | — | CN | claimed |
| US-20190099342-A1 | COOLING PRODUCT | SYMRISE AG (DE) | 2019-04-04 | — | — | US | claimed |
| US-20190083632-A1 | PLANT STEROIDS AND USES THEREOF | DAVIDSON LOPEZ LLC (US) | 2019-03-21 | — | — | US | claimed |
| CN-109234414-A | The PAS drug resistance diagnosis marker of mycobacterium tuberculosis and its application | 周琳 | 2019-01-18 | — | — | CN | claimed |
| CN-109078186-A | A kind of stomach floating composition and preparation method thereof | 江苏恒瑞医药股份有限公司 | 2018-12-25 | — | — | CN | claimed |
| US-20140220020-A1 | IL-1 BINDING PROTEINS | ABBVIE, INC. (US) | 2014-08-07 | — | — | US | claimed |
| EP-2172185-B1 | Cosmetic material comprising octyl hydroxy stearate oligomer | PARAHERMOSA CO LTD (JP) | 2011-11-23 | — | — | EP | claimed |
| WO-2011056948-A2 | METHODS OF TEXTURING SURFACES FOR CONTROLLED REFLECTION | ADVANCED TECHNOLOGY MATERIALS, INC. (US) | 2011-05-12 | — | — | WO | claimed |
| CN-101460060-A | Compositions and methods for topical treatment of tar-responsive skin disorders | TRISTRATA INC (US) | 2009-06-17 | — | — | CN | claimed |
| EP-1581206-A4 | TREATMENT OF INFLAMMATORY DISORDERS WITH 2,3-BENZODIAZEPINES | VELA ACQUISITION CORP (US) | 2009-01-07 | — | — | EP | claimed |
| US-20080131439-A1 | METHODS OF DIAGNOSING INFLAMMATORY BOWEL DISEASE | PROMETHEUS LABORATORIES INC. (US) | 2008-06-05 | — | — | US | claimed |
| EP-1581206-A1 | TREATMENT OF INFLAMMATORY DISORDERS WITH 2,3-BENZODIAZEPINES | Vela Pharmaceuticals Inc. (US) | 2005-10-05 | — | — | EP | claimed |
| EP-1568700-A1 | S-triazine derivatives containing at least two silated p-aminobenzalmalonate groups, sunscreen compositions containing these derivatives as well as the use of the derivatives | L'OREAL (FR) | 2005-08-31 | — | — | EP | claimed |
| US-20040138209-A1 | Treatment of inflammatory disorders with 2,3- benzodiazepines | VELA PHARMACEUTICALS, INC. | 2004-07-15 | — | — | US | claimed |
| WO-2004050080-A1 | TREATMENT OF INFLAMMATORY DISORDERS WITH 2,3-BENZODIAZEPINES | VELA PHARMACEUTICALS, INC. (US) | 2004-06-17 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040138209-A1 | Treatment of inflammatory disorders with 2,3- benzodiazepines | LTB4R2, LTB4R, GABRA4 | TSHR 327/4885LMNA 1715/4885HPGD 689/4885 |
| US-20190099342-A1 | COOLING PRODUCT | TRPA1, TRPV2, NISCH | TSHR 2965/4885LMNA 2013/4885HPGD 201/4885 |
| US-20190083632-A1 | PLANT STEROIDS AND USES THEREOF | CYP46A1, CYP17A1, NR1H4 | TSHR 3116/4885LMNA 4395/4885HPGD 645/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.