Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | CNR2 | P34972 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | TNF | P01375 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7651131 | 0.86 | CNR2 (0.42) | ALDH1A1CNR2LMNASMN1; SMN2KMT2A | |
| SCHEMBL7650555 | 0.85 | ALDH1A1 (0.35) | ALDH1A1CNR2LMNASMN1; SMN2KMT2A | |
| SCHEMBL7653503 | 0.81 | ALDH1A1 (0.37) | ALDH1A1CNR2SMN1; SMN2KMT2ATSHR | |
| SCHEMBL7650485 | 0.79 | HDAC1 (0.38) | ALDH1A1CNR2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7649498 | 0.79 | HDAC6 (0.40) | ALDH1A1CNR2SMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7648338 | 0.74 | FEN1 (0.45) | ALDH1A1SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL7655134 | 0.74 | TNF (0.51) | ALDH1A1CNR2LMNATNFNPC1 | |
| SCHEMBL7651184 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CNR2LMNAMAPK1TNF | |
| SCHEMBL7654850 | 0.73 | ALDH1A1 (0.50) | ALDH1A1CNR2LMNAMAPK1TNF | |
| SCHEMBL7652234 | 0.71 | CNR2 (0.49) | ALDH1A1CNR2LMNAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407116-B1 | 2,4-DIOXO-1,2,3,4-TETRAHYDROQUINAZOLINE DERIVATIVES; ANTIALLERGENS, ANTIASTHMATICS, ANTIHISTAMINES, AND ANTIINFLAMMATORY AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2002-06-18 | — | — | US | disclosed |
| EP-1026160-A1 | NITROGENOUS FUSED-RING COMPOUNDS, PROCESS FOR THE PREPARATION OF THE SAME, AND DRUGS | Takeda Chemical Industries, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |