Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.61 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | HTT | P42858 | 5/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.57 |
| ▸ | MEN1 | O00255 | 4/20 | 0.57 |
| ▸ | POLB | P06746 | 6/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 1/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.56 |
| ▸ | CA9 | Q16790 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.55 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.50 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1593502 | 0.89 | ALDH1A1 (0.76) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL1593930 | 0.82 | ALDH1A1 (0.67) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL16615503 | 0.82 | CA12 (0.61) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL1593422 | 0.82 | MEN1 (0.74) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL7652121 | 0.81 | POLB (0.60) | ALDH1A1MAPTHTTKMT2AMEN1 | |
| SCHEMBL7651587 | 0.78 | ALDH1A1 (0.63) | ALDH1A1MAPTHTTKMT2APOLB | |
| SCHEMBL2057475 | 0.77 | TDP1 (0.73) | MAPTHTTKMT2AMEN1POLB | |
| SCHEMBL6699009 | 0.76 | POLB (0.69) | ALDH1A1MAPTKMT2AMEN1POLB | |
| SCHEMBL4189849 | 0.74 | CA9 (0.68) | MAPTHTTKMT2AMEN1POLB | |
| SCHEMBL17947763 | 0.74 | CA9 (0.90) | MAPTHTTKMT2AMEN1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6407120-B1 | ADMINISTERING PYRIDINYLACETAMIDE OR PHENYLACETAMIDE DERIVATIVE TO TREAT CARDIOVASCULAR, EATING, SEXUAL, BRAIN, NERVOUS SYSTEM, GASTROINTESTINAL, UROGENITAL, PSYCHOLOGICAL, AND RESPIRATORY SYSTEM DISORDERS | PFIZER INC. | 2002-06-18 | — | — | US | disclosed |