Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.37 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | ESR1 | P03372 | 6/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | SHBG | P04278 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31505403 | 0.71 | CHRNB2 (0.44) | CHRNB2CHRNA4DRD2DRD3DRD4 | |
| SCHEMBL21959060 | 0.71 | MAOA (0.64) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL31505378 | 0.70 | MAOA (0.65) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL30645357 | 0.70 | MAOA (0.65) | DRD2DRD3DRD4 | |
| Bromide SCHEMBL21858250 | 0.70 | MAOA (0.65) | DRD2DRD3DRD4 | |
| SCHEMBL13799411 | 0.69 | DRD2 (0.50) | DRD2DRD3DRD4OPRM1OPRD1 | |
| SCHEMBL13049833 | 0.68 | ESR1 (0.53) | DRD2DRD3DRD4ESR1ESR2 | |
| SCHEMBL8034552 | 0.68 | ESR1 (0.53) | DRD2DRD3DRD4ESR1ESR2 | |
| SCHEMBL5325492 | 0.66 | CHRNB2 (0.39) | CHRNB2CHRNA4ESR1ESR2OPRM1 | |
| SCHEMBL28197625 | 0.66 | CHRNB2 (0.39) | CHRNB2CHRNA4ESR1ESR2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6482921-B1 | Uridyl peptide antibiotic (UPA) derivatives, their synthesis and use | ESSENTIAL THERAPEUTICS, INC. | 2002-11-19 | — | — | US | claimed |
| WO-2000044335-A2 | URIDYL PEPTIDE ANTIBIOTIC (UPA) DERIVATIVES, THEIR SYNTHESIS AND USE | MICROCIDE PHARMACEUTICALS, INC. (US) | 2000-08-03 | — | — | WO | claimed |