Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7106669 | 0.80 | PNP (0.41) | PNP | |
| SCHEMBL7656354 | 0.79 | PNP (0.36) | PNP | |
| SCHEMBL7661155 | 0.77 | CHRNB2 (0.38) | — | |
| SCHEMBL7109158 | 0.76 | PNP (0.46) | PNP | |
| SCHEMBL7656330 | 0.71 | ALDH1A1 (0.40) | — | |
| SCHEMBL7654642 | 0.70 | PNP (0.41) | PNP | |
| SCHEMBL7659642 | 0.69 | PNP (0.39) | PNP | |
| SCHEMBL7654547 | 0.68 | KMT2A (0.36) | PNP | |
| SCHEMBL7654381 | 0.67 | — | — | |
| SCHEMBL7663487 | 0.67 | PNP (0.34) | PNP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | claimed |
| US-6399613-B1 | N,N'-BIS(2-HYDROXYETHYL)PYRAZINE-2,5- OR -2,6-DICARBOXAMIDE; DIABETES | AVENTIS PHARMA S.A. (FR) | 2002-06-04 | — | — | US | disclosed |