SCHEMBL7652513

SCHEMBL7652513

Cc1cc[c]c(C#N)c1.[c]1ccccc1

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
CYP2A6 P11509 1/20 0.30
ACHE P22303 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL350245 0.90
SCHEMBL4622197 0.77 CYP2A6 (0.36) CYP2A6
SCHEMBL3995529 0.74 TSHR (0.39) ALDH1A1
SCHEMBL7647962 0.74 TRPA1 (0.33) ALDH1A1
SCHEMBL11600015 0.71 TDP1 (0.37) ALDH1A1
M-Xylene SCHEMBL10337433 0.71 ACHE (0.63) ALDH1A1ACHE
SCHEMBL8053955 0.70 ACHE (0.47) ALDH1A1CYP2A6ACHE
SCHEMBL455469 0.70
SCHEMBL6354657 0.69 NOTUM (0.36) ALDH1A1
SCHEMBL7874413 0.68 ALDH1A1 (0.36) ALDH1A1CYP2A6ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0973729-B1 A PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL DIPHENYL COMPOUNDS LUSO FARMACO INST (IT) 2002-09-11 EP disclosed
US-6111114-A Process for the preparation of 4-bromomethyl diphenyl compounds ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) 2000-08-29 US disclosed
EP-0973729-A1 A PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL DIPHENYL COMPOUNDS ISTITUTO LUSO FARMACO D'ITALIA S.p.A. (IT) 2000-01-26 EP disclosed
WO-1998046562-A1 A PROCESS FOR THE PREPARATION OF 4-BROMOMETHYL DIPHENYL COMPOUNDS ISTITUTO LUSO FARMACO D'ITALIA S.P.A. (IT) 1998-10-22 WO disclosed